2012年至今已发表的论文 1. Insights into quinaldic acid moiety formation in thiostrepton biosynthesis facilitating fluorinated thiopeptide generation. Lian Duan#; Shoufeng Wang#; Ri Jing Liao; Wen Liu*. Chem.Biol., 2012, 19, 443-448(IF: 6.64). 2. Opportunities and challenges from current investigations into the biosynthetic logic of nosiheptide-represented thiopeptide antibiotics. Shoufeng Wang; Shuai-xiang Zhou; Wen Liu*. Curr. Opin. Chem. Biol., 2013, 17, 626-634(IF:9.85). 3. Discovery and efficient synthesis of a biologically active alkaloid inspired by thiostrepton biosynthesis. Qing-Fei Zheng; Shoufeng Wang*; Wen Liu*. Tetrahedron, 2014, 70, 7686-7690(IF:2.64). 4. Target-oriented design and biosynthesis of thiostrepton-derived thiopeptide antibiotics with improved pharmaceutical properties. Shoufeng Wang#;Qingfei Zheng#;Jianfeng Wang; Zhixiong Zhao;Qingye Li;Yunsong Yu; Renxiao Wang; Wen Liu*. Org. Chem. Front., 2015, 2, 106–109(IF:4.69). 5. Thiopeptide antibiotics exhibit a dual mode of action against intracellular pathogens by affecting both host and microbe. Qingfei Zheng#; Qinglan Wang#; Shoufeng Wang#; Jiequn Wu; Qian Gao*; Wen Liu*. Chem. Biol., 2015, 22, 1002-1007(IF: 6.64). 6. Concurrent modifications of the C-terminus and side ring of thiostrepton and their synergistic effects with respect to improving antibacterial activities. Shoufeng Wang#*; Qingfei Zheng#; Jianfeng Wang; Dandan Chen; Yunsong Yu; Wen Liu*. Org. Chem. Front., 2016, 3, 496-500(IF:4.69). 7. Precursor-directed mutational biosynthesis facilitates the functional assignment of two cytochromes P450 in thiostrepton biosynthesis. Qingfei Zheng#; Shoufeng Wang#*; Rijing Liao; Wen Liu*. ACS Chem. Biol., 2016, 11, 2673−2678(IF:5.09). 8. An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization. Qingfei Zheng#, Shoufeng Wang#, Panpan Duan, Rijing Liao, Dandan Chen, Wen Liu*. Proc. Natl. Acad. Sci. USA., 2016, 113, 14318-14323(IF:10.28).
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